Quantum Dots (QDs)
Siarhei @ stock.adobe.com
Semiconductor nanoparticles with special optoelectronic properties which allow for real-time and highly sensitive tracking and imaging at molecular and cellular levels. New generations of QDs have been used to study intramolecular processes at a single-molecule level with high-resolution cellular imaging and long-term in vivo observation. By using UV-light or locally enhanced electromagnetic fields, it is possible to observe the photoluminescent change in the target in real-time or for high-resolution three-dimensional reconstructed imaging using adequate microscopes. QDs are much smaller in size and have been estimated to be 20 times brighter and 100 times more photostable than traditional fluorescent trackers.